Executive Director Clinical Development

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The position offers the opportunity to shape late‑stage clinical strategy, influence key regulatory decisions, and lead global, cross‑functional teams through critical development milestones.

Key Responsibilities • Lead the design, execution, and continuous evolution of the clinical development plan across Phase II/III and registration stages • Own the clinical strategy at programme level, contributing directly to the Target Product Profile, asset narrative, and value proposition • Drive late‑stage decision‑making, including study design, filing strategy, label considerations, and go/no‑go decisions • Translate complex clinical data into clear strategic insights to inform governance and portfolio decisions • Lead and develop a cross‑functional clinical team, including Clinical Program Leaders and scientific personnel, within a global matrix • Engage with senior governance bodies, providing recommendations to executive leadership and decision‑making committees • Represent the programme in interactions with global regulatory authorities (FDA, EMA), shaping regulatory strategy and supporting key submissions The Profile This role requires a clinical leader with deep expertise in metabolic disease and a proven track record of leading complex, late‑stage clinical development programmes.

Experience & Expertise • MD or PhD in a relevant scientific or medical discipline • ~6–10 years’ experience in clinical drug development within pharma and/or academia, ideally in an international setting • Demonstrated expertise in obesity, diabetes, or incretin‑based (GLP‑1) therapies • Significant recent experience leading Phase II/III and/or registration‑stage programmes, including: -Regulatory submissions and late‑stage strategic decision‑making (e.g. filing strategy, label positioning) -Strong understanding of the end‑to‑end product lifecycle, including pre‑launch and lifecycle management Why Join This role offers a rare opportunity to: • Take full ownership of a high‑profile clinical programme in one of the most dynamic and competitive therapy areas • Shape late‑stage strategy and regulatory positioning for assets with significant commercial and patient impact • Influence enterprise‑level decisions within a global organisation • Lead and develop a talented, international team in a scientifically driven environment If this opportunity aligns with your expertise and ambitions, we would welcome a confidential discussion.

We are partnering with a global, research‑driven pharmaceutical organisation to appoint an Executive Director Clinical development within its obesity and metabolic disease portfolio.

This is a senior leadership role with end‑to‑end accountability for the clinical development of a high‑priority asset, with particular focus on obesity, diabetes, and incretin‑based therapies. The Role You will define and execute a comprehensive clinical development strategy from post‑Proof of Concept through registration and lifecycle planning.

Operating at the centre of a global matrix, you will integrate clinical, regulatory, and commercial perspectives, ensuring the programme is scientifically robust, strategically differentiated, and positioned for long‑term value.